On 9 June 2021, the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) launched the European Drug Report 2021. The report delivers the most recent overview of the drug situation in Europe, based on data from 29 countries (27 Member States, Turkey, and Norway). Among other information, it recounts the lessons learned from the COVID-19 pandemic on how the pandemic has affected drug use and supply. It also provides a glance at Europe’s drug phenomena and the latest trends in drug production and drug trafficking. The report found, inter alia, that the drug market was rather resilient to the disruptions caused by the COVID-19 pandemic; criminals quickly adapted their trafficking measures and sale strategies. Levels of use of most drugs bounced back to pre-corona times when restrictions on travel, movement and social gatherings were eased in summer 2020. The report focuses on benzodiazepines on which specific concerns are raised regarding their misuse. The report lists several trends and invites politicians to discuss further reactions to new phenomena in drugs abuse and smuggling.