Six weeks after the European Public Prosecutor's Office (EPPO) started its operational and investigative activities, the body took stock of its work. In a brief press release dated 16 July 2021, the EPPO informed the public that it processed more than a thousand reports of fraud affecting the financial interests of the European Union. €7 million of goods were already seized.

On 14 September 2021, the Office informed the public that that it is currently investigating various suspected frauds having caused an estimated damage of almost €4.5 billion to the EU budget. Since 1 June 2021, the EPPO has registered more than 1700 crime reports from participating EU Member States and private parties and 300 investigations have been opened.