Between 8-19 November 2022, an operation conducted by law enforcement authorities from Belgium, France, the Netherlands, Spain, the United States, and the United Arab Emirates led to the take-down of a "super-cartel" controlling one third of cocaine trade in Europe. With the support of Europol's intelligence and analysis, the two-year investigation resulted in raids of the cartel’s command-and-control centre and its logistical drugs trafficking infrastructure in Europe, the arrests of 49 suspects in both territories (the EU and Dubai), and the seizure of more than 30 tonnes of drugs.

Europol supported the global operation by several measures, inter alia, by developing reliable intelligence on the drug trafficking cartel, identifying encrypted communication networks of the cartel, hosting multiple coordination meetings, and facilitating coordination in real time among all the partners involved.